Extraordinary Measures

The 2010 American medical drama directed by Tom Vaughan and written by Robert Nelson Jacobs is based on the true story of John and Aileen Crowley, whose two children suffer from Pompe disease, a rare genetic disorder. John Crowley (Brendan Fraser), a successful marketing executive, seeks a cure for his children and partners with Dr. Robert Stonehill (Harrison Ford), an unconventional scientist researching enzyme therapy. Together, they establish a biotech company, navigating venture capital challenges, bureaucratic hurdles, scientific obstacles, and personal conflicts. The film delves into the intricacies of drug development, highlighting the tension between scientific ideals and commercial interests, as well as the emotional journey of the Crowley family. The cast also includes Keri Russell (Aileen Crowley), Meredith Droeger (Megan Crowley), Diego Velazquez (Patrick Crowley), Jared Harris (Dr. Kent Webber), Patrick Bauchau (Eric Loring), Alan Ruck (Pete Sutphen), and David Clennon (Dr. Renzler). Filming took place in various locations across Oregon and Washington. With a budget of $31 million, the film grossed approximately $15 million worldwide.